Nattokinase: A Natural Enzyme for Cardiovascular Health
Nattokinase, an enzyme derived from the traditional Japanese dish natto (fermented soybeans), has been gaining attention for its potential health benefits, particularly in the realm of cardiovascular health. This unique enzyme is celebrated for its fibrinolytic (clot-dissolving) properties and its potential to improve circulation and support overall heart health. Below, we will look into what nattokinase is, how it works, its potential benefits, and important considerations for its use.
What is Nattokinase?
Nattokinase is an enzyme produced during the fermentation of soybeans with the bacterium Bacillus subtilis natto. This fermentation process not only gives natto its distinctive flavour and texture but also produces this powerful enzyme. Nattokinase has been used in traditional Japanese medicine for centuries, but its therapeutic potential was first scientifically identified in the 1980s by Dr. Hiroyuki Sumi, who named the enzyme "nattokinase."
How Does Nattokinase Work?
Nattokinase is a natural fibrinolytic agent, meaning it has the ability to break down fibrin, a protein involved in blood clot formation. It mimics the body's own plasmin, an enzyme responsible for dissolving clots. By breaking down fibrin, nattokinase can help improve blood flow and reduce the risk of clot-related health issues such as stroke, deep vein thrombosis (DVT), and pulmonary embolism.
Potential Health Benefits of Nattokinase
1. Blood Clot Prevention
Nattokinase is perhaps best known for its potential to prevent blood clots. Research suggests that it can enhance the body’s natural ability to dissolve clots, making it a promising option for individuals at risk of cardiovascular events. A study published in the journal Acta Haematologica in 2016 found that nattokinase could effectively dissolve blood clots in patients with deep vein thrombosis.
2. Improved Circulation and Blood Flow
By reducing blood viscosity and breaking down small clots, nattokinase may help improve overall circulation. Better circulation can support heart health and reduce the risk of complications associated with poor blood flow. A PubMed study in 2013 concluded that Nattokinase improves blood flow by inhibiting platelet aggregation and thrombus formation.
3. Blood Pressure Regulation
Some studies indicate that nattokinase may help lower blood pressure by improving blood flow and reducing arterial stiffness. This can further support cardiovascular health and reduce the risk of hypertension-related complications.
A study published in the Journal of Hypertension in 2008 concluded that nattokinase supplementation led to significant reductions in both systolic and diastolic blood pressure among people with hypertension.
4. Potential Stroke and Heart Attack Prevention
By addressing factors like clot formation and high blood pressure, nattokinase may play a role in reducing the risk of serious cardiovascular events such as strokes and heart attacks.
Two recent studies here and here show potential for use of nattokinase in the prevention and treatment of diseases such as vascular disease and ischemic stroke and TIA.
According to this study Nattokinase provided better atherosclerosis management than statins.
Safety and Considerations
Although nattokinase is generally considered safe for most people, there are some important precautions to keep in mind:
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Risk of Bleeding: Nattokinase has blood-thinning properties, which may increase the risk of bleeding, particularly in individuals taking anticoagulant or antiplatelet medications.
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Medical Supervision: People with bleeding disorders, low blood pressure, or those scheduled for surgery should consult a healthcare provider before using nattokinase.
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Pregnancy and Breastfeeding: There is limited research on the safety of nattokinase during pregnancy or breastfeeding, so it is best avoided unless advised by a doctor.
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Dosage and Quality: It is important to use high-quality nattokinase supplements from reputable manufacturers. Follow recommended dosages and consult a healthcare provider for personalised advice.
Conclusion
Nattokinase is a promising natural enzyme with potential benefits for cardiovascular health. Its ability to dissolve fibrin and improve circulation makes it a valuable tool in supporting heart health and preventing blood clots.
As with any supplement, it is crucial to consult a healthcare professional before starting nattokinase, especially if you have existing health conditions or are taking medications. With proper guidance, nattokinase could be a beneficial addition to a heart-healthy lifestyle.
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